Lednicer D. Steroid Chemistry at a Glance

John Wiley & Sons Ltd, 2011. — 144 p. - (At a Glance)Steroids: a Brief History
Structure Determination
Cholesterol and Cholic Acid
The Sex Steroids
Corticosteroids
Sources of Steroids
Biosynthesis
Commercial Steroid Starting Materials
Diosgenin
Soybean Sterols
Estranes: Steroids in Which Ring A is Aromatic
Biological Activity
Sources of Estranes
From Androstanes
Estrogens by Total Synthesis
Chemical Reactions of Estranes
Aromatic A-ring Reactions
Modifications on Ring B
Modifications on Ring C
Modifications on Ring D
Some Drugs Based on Estranes
Gonanes or 19-nor-Steroids
Preparation of Gonane Starting Materials
Synthesis by Sequential Annulation Reactions
Anabolic–Androgenic Gonanes
Biological Activity
Synthesis of 19-Norandrogens
Progestational Gonanes
Biological Activity
Preparation of 19-Norprogestins
Some Drugs Based on Gonanes
Androgenic–Anabolic Agents
Progestins
Progestin Antagonists
Androstanes, C19 Steroids and Their Derivatives
Biological Activity
Sources of Androstanes
From Pregnenolone
Fermentations
Total Synthesis
Modified Anabolic–Androgenic Androstanes
17-Desalkyl Compounds
17-Alkyl Compounds
Modifications on Ring B
Modifications on Ring C
Modifications on Ring D
17-Spirobutyrolactone Aldosterone Antagonists
Some Drugs Based on Androstanes
Androgens
Spirobutyrolactones
Pregnanes, Part 1: Progestins
Biological Activity
Sources of Progesterone
From Phytochemicals
By Total Synthesis
From Dehydroepiandrosterone (DHEA) Acetate
Modified Pregnanes
17-Hydroxy and Acyloxy Derivatives
Modifications on Ring A
Modifications on Ring B
General Methods for Modifications on Ring D
More Progesterone Analogues
Some Drugs Based on Progestins
Medroxyprogesterone Acetate (10-2)
Megestrol Acetate (10-3)
Melengestrol Acetate (26-7)
Pregnanes, Part 2: Corticosteroids
Biological Activity
Sources of Corticoids
Introduction of Oxygen at C11
Construction of the Dihydroxyacetone Side Chain
Modified Corticoids
Unsaturation
Additional Alkyl Groups
Halogenated Corticoids
Hydroxylation: 16,17-Diols
Corticoids with Multiple Modifications
Miscellaneous Corticoids
Some Drugs Based on Corticoids
Miscellaneous Steroids
Heterocyclic SteroidsSteroids with a Heteroatom in Ring A
Steroids with a Heteroatom in Ring B
Steroids with a Heteroatom in Ring C
Steroids with a Heteroatom in Ring D
Cardenolides
Actodigin Aglycone
Synthesis from a Bile Acid
Compounds Related to Cholesterol
Subject Index
Reactions Index