Murray R.K., Granner D.K., Mayes P.A., Rodwell V.W. Harper's Illustrated Biochemistry

26th edition. The McGraw-Hill Companies, Inc. 2003. - 693 p.
The text is divided into two introductory chapters (Biochemistry & Medicine and Water & pH) followed by six main sections.Section I deals with the structures and functions of proteins and enzymes, the workhorses of the body. Because almost all of the reactions in cells are catalyzed by enzymes, it is vital to understand the properties of enzymes before considering other topics.Section II explains how various cellular reactions either utilize or release energy, and it traces the pathways by which carbohydrates and lipids are synthesized and degraded. It also describes the many functions of these two classes of molecules.Section III deals with the amino acids and their many fates and also describes certain key features of protein catabolism.Section IV describes the structures and functions of the nucleotides and nucleic acids, and covers many major topics such as DNA replication and repair, RNA synthesis and modification, and protein synthesis. It also discusses new findings on how genes are regulated and presents the principles of recombinant DNA technology.Section V deals with aspects of extracellular and intracellular communication. Topics covered include membrane structure and function, the molecular bases of the actions of hormones, and the key field of signal transduction.Section VI consists of discussions of eleven special topics: nutrition, digestion, and absorption; vitamins and minerals; intracellular traffic and sorting of proteins; glycoproteins; the extracellular matrix; muscle and the cytoskeleton; plasma proteins and immunoglobulins; hemostasis and thrombosis; red and white blood cells; the metabolism of xenobiotics; and the Human Genome Project.AuthorsBiochemistry & Medicine
Robert K. Murray, MD, PhDWater & pH
Victor W. Rodwell, PhD, & Peter J. Kennelly, PhDSECTION I. STRUCTURES & FUNCTIONS OF PROTEINS & ENZYMESAmino Acids & Peptides
Victor W. Rodwell, PhD, & Peter J. Kennelly, PhDProteins: Determination of Primary Structure
Victor W. Rodwell, PhD, & Peter J. Kennelly, PhDProteins: Higher Orders of Structure
Victor W. Rodwell, PhD, & Peter J. Kennelly, PhDProteins: Myoglobin & Hemoglobin
Victor W. Rodwell, PhD, & Peter J. Kennelly, PhDEnzymes: Mechanism of Action
Victor W. Rodwell, PhD, & Peter J. Kennelly, PhDEnzymes: Kinetics
Victor W. Rodwell, PhD, & Peter J. Kennelly, PhDEnzymes: Regulation of Activities
Victor W. Rodwell, PhD, & Peter J. Kennelly, PhDSECTION II. BIOENERGETICS & THE METABOLISM OF CARBOHYDRATES & LIPIDSBioenergetics: The Role of ATP
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScBiologic Oxidation
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScThe Respiratory Chain & Oxidative Phosphorylation
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScCarbohydrates of Physiologic Significance
Peter A. Mayes, PhD, DSc, & David A. Bender, PhDLipids of Physiologic Significance
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScOverview of Metabolism
Peter A. Mayes, PhD, DSc, & David A. Bender, PhDThe Citric Acid Cycle: The Catabolism of Acetyl-CoA
Peter A. Mayes, PhD, DSc, & David A. Bender, PhDGlycolysis & the Oxidation of Pyruvate
Peter A. Mayes, PhD, DSc, & David A. Bender, PhDMetabolism of Glycogen
Peter A. Mayes, PhD, DSc, & David A. Bender, PhDGluconeogenesis & Control of the Blood Glucose
Peter A. Mayes, PhD, DSc, & David A. Bender, PhDThe Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism
Peter A. Mayes, PhD, DSc, & David A. Bender, PhDBiosynthesis of Fatty Acids
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScOxidation of Fatty Acids: Ketogenesis
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScMetabolism of Unsaturated Fatty Acids & Eicosanoids
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScMetabolism of Acylglycerols & Sphingolipids
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScLipid Transport & Storage
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScCholesterol Synthesis, Transport, & Excretion
Peter A. Mayes, PhD, DSc, & Kathleen M. Botham, PhD, DScIntegration of Metabolism – the Provision of Metabolic Fuels
David A. Bender, PhD, & Peter A. Mayes, PhD, DSc.SECTION III. METABOLISM OF PROTEINS & AMINO ACIDSBiosynthesis of the Nutritionally Nonessential Amino Acids
Victor W. Rodwell, PhD
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Catabolism of Proteins & of Amino Acid Nitrogen
Victor W. Rodwell, PhDCatabolism of the Carbon Skeletons of Amino Acids
Victor W. Rodwell, PhDConversion of Amino Acids to Specialized Products
Victor W. Rodwell, PhDPorphyrins & Bile Pigments
Robert K. Murray, MD, PhD
SECTION IV. STRUCTURE, FUNCTION, & REPLICATION OF INFORMATIONAL MACROMOLECULES

Nucleotides
Victor W. Rodwell, PhDMetabolism of Purine & Pyrimidine Nucleotides
Victor W. Rodwell, PhDNucleic Acid Structure & Function
Daryl K. Granner, MD
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DNA Organization, Replication, & Repair
Daryl K. Granner, MD, & P. Anthony Weil, PhDRNA Synthesis, Processing, & Modification
Daryl K. Granner, MD, & P. Anthony Weil, PhDProtein Synthesis & the Genetic Code
Daryl K. Granner, MDRegulation of Gene Expression
Daryl K. Granner, MD, & P. Anthony Weil, PhDMolecular Genetics, Recombinant DNA, & Genomic Technology
Daryl K. Granner, MD, & P. Anthony Weil, PhDSECTION V. BIOCHEMISTRY OF EXTRACELLULAR & INTRACELLULAR COMMUNICATION

Membranes: Structure & Function
Robert K. Murray, MD, PhD, & Daryl K. Granner, MDThe Diversity of the Endocrine System
Daryl K. Granner, MDHormone Action & Signal Transduction
Daryl K. Granner, MDSECTION VI. SPECIAL TOPICS

Nutrition, Digestion, & Absorption
David A. Bender, PhD, & Peter A. Mayes, PhD, DScVitamins & Minerals
David A. Bender, PhD, & Peter A. Mayes, PhD, DScIntracellular Traffic & Sorting of Proteins
Robert K. Murray, MD, PhDGlycoproteins
Robert K. Murray, MD, PhDThe Extracellular Matrix
Robert K. Murray, MD, PhD, & Frederick W. Keeley, PhDMuscle & the Cytoskeleton
Robert K. Murray, MD, PhDPlasma Proteins & Immunoglobulins
Robert K. Murray, MD, PhDHemostasis & Thrombosis
Margaret L. Rand, PhD, & Robert K. Murray, MD, PhDRed & White Blood Cells
Robert K. Murray, MD, PhDMetabolism of Xenobiotics
Robert K. Murray, MD, PhD
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The Human Genome Project
Robert K. Murray, MD, PhDAppendix