Walter de Gruyter GmbH, 2021. — 380 p. — ISBN 978-3-11-063579-9
This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well.
Methods for the synthesis of oligonucleotides
Synthesis of oligonucleotides carrying DNA lesions for DNA repair studies
Synthesis of oligonucleotides carrying modified bases for DNA and protein recognition
Nonradioactive labeling of oligonucleotides and postsynthetic modification of oligonucleotides
Nucleic acids triple helices
Nucleic acids quadruplex
Advances in therapeutic oligonucleotide chemistry
Oligonucleotide conjugates and DNA nanotechnology