Hurlemann Rene, Grinevich Valery (eds.) Behavioral Pharmacology of Neuropeptides: Oxytocin

Springer, 2018. — 586 p. — (Current Topics in Behavioral Neurosciences. Vol. 35).This volume collects cutting-edge expert reviews in the oxytocin field and will be of interest to a broad scientific audience ranging from social neuroscience to clinical psychiatry. The role of the neuropeptide oxytocin in social behaviors is one of the earliest and most significant discoveries in social neuroscience. Influential studies in animal models have delineated many of the neural circuits and genetic components that underlie these behaviors. These discoveries have inspired researchers to investigate the effects of oxytocin on brain and behavior in humans and its potential relevance as a treatment for psychiatric disorders including borderline personality disorder and autism and schizophrenia spectrum disorders. In fact, there is no established social psychopharmacology in Psychiatry, and oxytocin can be seen as the first endogenous agent specifically addressing social-cognitive impairment in psychiatric disorders, with animal research suggesting that it could be especially efficient in the early postnatal period. From a human perspective, it is crucial to understand more precisely who can benefit from potential oxytocin-related treatments, which outcome measures will best represent their effects, how they should be administered, and what brain mechanisms are likely involved in mediating their effects. This type of “precision medicine” approach is in line with the research domain criteria defined by the U.S. National Institute of Mental Health.Animal Research Section
Molecular Basis of Oxytocin Receptor Signalling in the Brain: What We Know and What We Need to Know
Oxytocin Modulation of Neural Circuits
Oxytocin and Olfaction
Oxytocin and Steroid Actions
Oxytocin and Social Relationships: From Attachment to Bond Disruption
Oxytocin and Parental Behaviors
The Role of Oxytocin in Social Buffering: What Do Primate Studies Add?
Oxytocin and Aggression
Oxytocin Signaling in Pain: Cellular, Circuit, System, and Behavioral Levels
Oxytocin and Animal Models for Autism Spectrum Disorder
Oxytocin Signaling in the Early Life of Mammals: Link to Neurodevelopmental Disorders Associated with ASD
The Multidimensional Therapeutic Potential of Targeting the Brain Oxytocin System for the Treatment of Substance Use Disorders
Human Research Section
Oxytocin and Human Evolution
Overview of Human Oxytocin Research
Oxytocin and Facial Emotion Recognition
Oxytocin and Social Cognition
Oxytocin and Interpersonal Relationships
Oxytocin and Human Sensitive and Protective Parenting
Oxytocin and Autism Spectrum Disorders
Oxytocin and Anxiety Disorders
Oxytocin and Borderline Personality Disorder
Oxytocin and Schizophrenia Spectrum Disorders
Oxytocin and Prader-Willi Syndrome
A Precision Medicine Approach to Oxytocin Trials
Erratum to: Oxytocin Signaling in Pain: Cellular, Circuit, System, and Behavioral Levels
Erratum to: Oxytocin Signaling in the Early Life of Mammals: Link to Neurodevelopmental Disorders Associated with ASD