Lenarz Th., Wriggers P. (eds.) Biomedical technology: modeling, experiments and simulation

New York: Springer, 2018. — 356 p.This book provides an overview of new mathematical models, computational simulations and experimental tests in the field of biomedical technology, and covers a wide range of current research and challenges. The first part focuses on the virtual environment used to study biological systems at different scales and under multiphysics conditions. In turn, the second part is devoted to modeling and computational approaches in the field of cardiovascular medicine, e.g. simulation of turbulence in cardiovascular flow, modeling of artificial textile-reinforced heart valves, and new strategies for reducing the computational cost in the fluid-structure interaction modeling of hemodynamics. The book’s last three parts address experimental observations, numerical tests, computational simulations, and multiscale modeling approaches to dentistry, orthopedics and otology. Written by leading experts, the book reflects the remarkable advances that have been made in the field of medicine, the life sciences, engineering and computational mechanics over the past decade, and summarizes essential tools and methods (such as virtual prototyping of medical devices, advances in medical imaging, high-performance computing and new experimental test devices) to enhance medical decision-making processes and refine implant design. The contents build upon the International Conference on Biomedical Technology 2015 (ICTB 2015), the second ECCOMAS thematic conference on Biomedical Engineering, held in Hannover, Germany in October 2015.Multiscale Aspects in the Multiphasic Modelling of Human Brain Tissue
Simulation of Steatosis Zonation in Liver Lobule—A Continuummechanical Bi-Scale, Tri-Phasic, Multi-Component Approach
Nano-Mechanical Tensile Behavior of the SPTA1 Gene in the Presence of Hereditary Hemolytic Anemia-Related Point Mutations
The Choice of a Performance Indicator of Release in Transdermal Drug Delivery SystemsMultiscale Multiphysic Approaches in Vascular Hemodynamics
Heart Valve Flow Computation with the Space–Time Slip Interface Topology Change (ST-SI-TC) Method and Isogeometric Analysis (IGA)
Estimation of Element-Based Zero-Stress State in Arterial FSI Computations with Isogeometric Wall Discretization
Fluid-Structure Interaction Modeling in 3D Cerebral Arteries and Aneurysms
Large-Eddy Simulation of Turbulence in Cardiovascular Flows
Computational Comparison Between Newtonian and Non-Newtonian Blood Rheologies in Stenotic Vessels
Artificial Textile Reinforced Tubular Aortic Heart Valves—Multi-scale Modelling and Experimental Validation
Preliminary Monolithic Fluid Structure Interaction Model for Ventricle Contraction
The Biomechanical Rupture Risk Assessment of Abdominal Aortic Aneurysms—Method and Clinical RelevanceA Deeper Insight of a Multi-dimensional Continuum Biofilm Growth Model: Experimental Observation and Parameter Studies
Multiscale Experimental and Computational Investigation of Nature’s Design Principle of Hierarchies in Dental EnamelChallenges in Total Hip Arthroplasty
Personalized Orthopedic Trauma Surgery by Applied Clinical MechanicsMeasurement of Intracochlear Pressure Differences in Human Temporal Bones Using an Off-the-Shelf Pressure Sensor
Development of a Parametric Model of the Electrically Stimulated Auditory Nerve