Chapman and Hall/CRC, 2016. — 216 p. — (Chapman & Hall/CRC Biostatistics). — ISBN: 1466505753, 9781466505759
Adaptive experimental designs are sequential procedures for collecting data. In each step, the observer can use all of the information gathered to determine whether to stop or carry on with the study. This book focuses on recently developed methods in adaptive randomization for treatment allocation. It illustrates designs that take into account past treatment allocations only, discusses procedures that use past data, and presents compromise strategies that deal with ethical issues.