Hulley S.B., Cummings S.R., Browner W.S., Newman T.B. Designing Clinical Research

Philadelphia: Wolters Kluwer, 2013. - 381p.Designing Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involved in designing, funding, and implementing. New to this edition: Expanded and updated content in every chapter, with new material on: non-inferiority trials for comparative effectiveness research; incidence-density case-control studies; confounding and effect modification; diagnostic test studies to inform prediction rules; ethical aspects of whole genome sequencing; automated data management approaches; new NIH grant-writing requirements n Color format, and Electronic access, powered by Inkling[trademark] as a free companion to the text; viewable through your browser or as a download to tablet or smartphone; the complete text with optimized navigation; note-sharing, highlighting and bookmarking capability; cross-linking of references and content; and, rapid search options linked to the new glossary.