Kulka M. Using Old Solutions to New Problems: Natural Drug Discovery in the 21st Century

2th ed. InTech 2015. — 424 p.
ISBN10: 953-51-1158-2.
ISBN13: 978-953-51-1158-0.
This book is a collection of an expert team of agronomists, chemists, biologists and policy makers who discuss some of the processes involved in developing a naturally-sourced bioactive compound into a drug therapy. These experts define a natural compound and elucidate the processes required to find, extract and define a naturally-derived bioactive molecule, they describe the necessity for understanding the fundamental mechanisms of disease before applying bioactive molecules in bioassay-guided drug discovery platforms.
The medicinal use of plants, animals and microorganisms has been a part of human evolution and likely began before recorded history. Is it possible that this knowledge can be used to create powerful new drugs and solve some of the human health problems facing us today?Section 1 Agronomy and Molecular Characterization.
1 Discovery, Development, and Regulation of Natural Products.
2 Genetic, Agronomy, and Metabolomics of Prince Edwards Island Wild Rose Collection and Promise for Cultivar Development.
3 Magnetic Resonance Technologies: Molecules to Medicine.
Section 2 Bioactive Proteins from Natural Sources.
4 Marine Natural Products for Protein Misfblding Modulation.
5 Marine Flatfish-Derived Bioactive Peptides: From the Ocean to the Bedside.
Section 3 Bioactive Ingredients in Nutrition.
6 Anticancer Properties of Phytochemicals Present in Medicinal Plants of North America.
7 A New Perspective on the Development of Cholesterol-Lowering Products.
8 A Glance at the Complexity of Nutrition and the Prostate: Considering Molecular Targets to Unravel the Most Recent Controversy Between Omega-3 Fatty Acids and Their Impact on Prostate Cancer Risk.
Section 4 Bioactive Compounds in Health and Disease.
9 Mechanisms and Treatment of Photoaging and Photodamage.
10 Asthma in the 21st Century — Unexpected Applications of Ancient Treatments.
11 Plant Based Natural Products and Breast Cancer: Considering Multi-Faceted Disease Aspects, Past Successes, and Promising Future Interventions.